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PHYL Acts to Down-Regulate TTK88, a Transcriptional Repressor of ...

We show that Tramtrack (TTK88) expression represses neuronal fate determination in the developing Drosophila eye. Phyllopod (PHYL) acts to antagonize this ...
www.sciencedirect.com/science/article/pii/S0092867...

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Sep 17, 2007 ... used by SinaH is specific for the Ttk69 isoform and is distinct from that used to recognize Ttk88. Tramtrack proteins have been demonstrated to ...
www.jbc.org/content/283/2/1076.full.pdf

Seven-in-absentia protein, TRAF-like domain (IPR018121 ...

Through this domain, Sina binds E2 ubiquitin-conjugating enzymes (UbcD1) Sina also interacts with Tramtrack (TTK88) via PHYL. Tramtrack is a transcriptional ...
www.ebi.ac.uk/interpro/entry/IPR018121

Tramtrack69 Is Positively and Autonomously Required for ...

eye development. Consistent with this notion, the Ttk69 protein, but not Ttk88, is expressed in all photoreceptor cells during pupal stage. Thus, Ttk69 appears to ...
www.ncbi.nlm.nih.gov/pmc/articles/.../pdf/10224262...

ED negatively regulates EGFR signaling

differentiation. TTK88 functions as a transcriptional repressor to inhibit photoreceptor but not cone cell differentiation (Lai et al., 1996; Yamamoto et al., 1996).
genetics.med.harvard.edu/~perrimon/papers/baidev.p...

R7 Photoreceptor Axon Growth Is Temporally Controlled by the ...

The ttk locus encodes two transcription factor isoforms, Ttk69 and Ttk88, which ... We found that overexpressing Ttk88 had no effect on ttk1e11 mutant R7s (Fig.
www.ncbi.nlm.nih.gov/pmc/articles/PMC3739876/

Degrading liaisons: Siah structure revealed

(PHYL) to degrade the transcriptional repressor Tramtrack (TTK88)1,12. The Siah proteins of mam- mals have been implicated in regulating polyubiquitination ...
www.nature.com/nsmb/journal/v9/n1/pdf/nsb0102-8.pd...

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Ttk88 uses the REST corepressor Drosophila CoREST to coordi- nately regulate a set of genes encoding the same neuronal hallmarks that are regulated by ...
www.jneurosci.org/content/24/32/7186.full.pdf

PHYL Acts to Down-Regulate TTK88, a Transcriptional Repressor of ...

Figure 1. Ectopic Expression of TTK88 Blocks Neuronal Development. Scanning electron micrographs (A and B) of adult eyes, apical sections through adult ...
www.cell.com/abstract/S0092-8674(00)80506-1

ttk tramtrack [ (fruit fly)]

4 days ago ... ... Ttk88 repressor, enhancer of yan at 100D, oversensitive, schmal, tramtrack-69, tramtrak, ttk-PA, ttk-PB, ttk-PC, ttk-PD, ttk-PE, ttk-PF, ttk-PG, ttk- ...
www.ncbi.nlm.nih.gov/gene/48317